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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SON All Species: 8.79
Human Site: S1774 Identified Species: 38.67
UniProt: P18583 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18583 NP_115571.1 2426 263846 S1774 A A S P V V S S M P E R A S E
Chimpanzee Pan troglodytes XP_001165975 2426 263766 S1774 A A S P V V S S M P E R A S E
Rhesus Macaque Macaca mulatta XP_001093086 2187 237232 E1617 G R R S V S K E K R K R S P K
Dog Lupus familis XP_857313 2314 250877 A1740 E R L T S L R A G I E G P L L
Cat Felis silvestris
Mouse Mus musculus Q9QX47 2404 261412 S1759 A A S P V V I S I P E R A S E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513874 2213 236747 E1643 S K R S K S S E H K S R R R T
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 86.4 86.1 N.A. 85.2 N.A. N.A. 57 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 87.1 89.1 N.A. 89.5 N.A. N.A. 64.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 6.6 N.A. 86.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 20 N.A. 93.3 N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 50 0 0 0 0 0 17 0 0 0 0 50 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 17 0 0 0 0 0 0 34 0 0 67 0 0 0 50 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 0 0 0 0 0 0 17 0 0 17 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 17 0 17 17 0 0 0 0 0 % I
% Lys: 0 17 0 0 17 0 17 0 17 17 17 0 0 0 17 % K
% Leu: 0 0 17 0 0 17 0 0 0 0 0 0 0 17 17 % L
% Met: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 50 0 0 0 0 0 50 0 0 17 17 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 34 34 0 0 0 17 0 0 17 0 84 17 17 0 % R
% Ser: 17 0 50 34 17 34 50 50 0 0 17 0 17 50 0 % S
% Thr: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 17 % T
% Val: 0 0 0 0 67 50 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _